Lorin Bachmann, PhD, DABCC
Co-Director of Clinical Chemistry; Professor
Director of Blood Gas Laboratory;
Director of New Kent Emergency Department Laboratory;
Associate Director of Pathology Information Systems;
Technical Director of Clinical Pathology Research Services
Department: Pathology
Phone: (804) 828-6407
Email: Lorin.Bachmann@vcuhealth.org
Lorin Bachmann, PhD, DABCC, joined the VCU Department of Pathology in 2007. In addition to VCU service responsibilities listed above, Dr. Bachmann also serves as the Technical Director for the VCUH Anesthesiology Laboratory, Technical Director for the VCUH Clinical Pathology Research Services, and Laboratory Director for multiple VCUHS outreach laboratories.
Dr. Bachmann received a PhD in Molecular Medicine from the University of Virginia, followed by a fellowship in clinical chemistry and proteomics research at the University of Virginia. She is certified by the American Board of Clinical Chemistry. Dr. Bachmann is a member of the Clinical and Laboratory Standards Institute (CLSI) Board of Directors, the College of American Pathologists (CAP) Standards Committee, and the joint National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/International Federation of Clinical Chemistry Laboratory (IFCC) Joint Working Group on Standardization of Urine Albumin Assays. She also serves as an Advisor for the CLSI Expert Panel on Clinical Chemistry and Toxicology. Dr. Bachmann’s research interests include evaluation of new clinical laboratory assays, translation of biomarker assays to the clinical laboratory, clinical laboratory analyzer design and standardization of laboratory testing. Dr. Bachmann has received numerous awards for her contributions to professional societies, education, and research.
Clinical Specialties: Clinical Chemistry and Laboratory Medicine, Point-of-Care Testing, Clinical and Translational Research
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Dr. Lorin Bachmann abbreviated CV
Education
2007 Clinical Chemistry and Laboratory Medicine Fellow, University of Virginia, Charlottesville, VA
2005 PhD, Molecular Medicine, University of Virginia, Charlottesville, VA
2005 Biotechnology Training Program Fellow, University of Virginia, Charlottesville, VA
1996 BS, Biology/Medical Technology, Virginia Tech, Blacksburg, VA
Licenses & Certifications
2008 Diplomate of the American Board of Clinical Chemistry (DABCC)
1996 American Society of Clinical Pathologists (ASCP), Medical Technologist (MT)
Selected Awards & Honors
2025 Certificate of Appreciation: College of American Pathology (CAP). Awarded for contributions to the CAP Accuracy Based Programs Committee
2022 CLSI Service Award: Clinical and Laboratory Standards Institute (CLSI). Awarded for contributions to CLSI C62 guidelines document, Liquid Chromatography Mass Spectrometry Methods
2019 Plenary Lecture Award: Clinical and Pharmaceutical Solutions through Analysis (CPSA). Awarded for contributions in clinical analysis across disciplines
2017 Outstanding Speaker Award: American Association for Clinical Chemistry (AACC)
2017 Excellence in Education Award: American Association for Clinical Chemistry
2016 CLSI Service Award: Clinical and Laboratory Standards Institute (CLSI). Awarded for contributions to CLSI C57 guidelines document, Mass Spectrometry for Androgen and Estrogen in Serum
Recent Grants & Funding
Former Grants
Evaluation of Use of Single Donor Urine Specimens for Commutability Assessment of Reference Materials for Development of Reference Measurement Systems for Urine Albumin.
Sponsor: National Institutes of Standards and Technology (NIST).
Role: Principal Investigator 7/17/2023-7/16/2024
Alinity i Transplant Assay Clinical Evaluation Protocol.
Sponsor: Abbott Laboratories.
Role: Principal Investigator 5/16/2019-2021
Alinity i STAT hsTnI Design Validation.
Sponsor: Abbott Laboratories.
Role: Principal Investigator 1/1/19-12/8/20
Evaluation of Harmonization of Urine Albumin Measurement.
Sponsor: National Kidney Disease Education Program (NKDEP)/National Institutes of Diabetes and Kidney Disease (NIDDK)
Role: Principal Investigator 5/1/2010-4/3/2012
Professional Service (outside)
2026 - present Member, Document Development Committee, Clinical and Laboratory Standards Institute (CLSI), CLSI EP50, Evaluation of Stability for Venous Whole Blood and Blood Derived Samples, 1st Edition. Appointed.
2026 - present Member (2nd Term), Board of Directors, Clinical Laboratory and Standards Institute (CLSI). Elected.
2026 - present Advisor, Clinical Laboratory and Standards Institute (CLSI) Expert Panel on Clinical Chemistry and Toxicology. Appointed.
2025 - present Member, Document Development Committee, Clinical and Laboratory Standards Institute (CLSI), CLSI QMS30, Good Clinical Practice (GCP) for Participation in Clinical Studies and Trials. Appointed.
2025 - present Member, Clinical Laboratory and Standards Institute (CLSI) Finance Committee. Appointed.
2025 - present Scientific Session Planning Committee Member, 2026 Annual Meeting Organizing Committee, Association for Diagnostics and Laboratory Medicine (ADLM). Appointed.
2025 - present Member, College of American Pathology Standards Committee. Appointed.
2022 - present Member, Document Development Committee, Clinical and Laboratory Standards Institute (CLSI), CLSI C46, Blood Gas and pH Analysis and Related Measurements, Third Ed. Appointed.
2021 - present Member, Document Development Committee, Clinical and Laboratory Standards Institute (CLSI), CLSI EP45, Implementation of Reference Intervals in the Medical Laboratory. Appointed.
2019 - present Member, National Institute of Diabetes and Digestive and Kidney Diseases/International Federation of Clinical Chemistry Laboratory Joint Working Group (NIDDK/IFCC LWG) for Standardization of Urine Albumin. Appointed.
2023 - 2025 Member (1st Term), Board of Directors, Clinical Laboratory and Standards Institute (CLSI). Elected.
2023 - 2025 Member, Clinical Laboratory and Standards Institute (CLSI) Expert Panel on Clinical Chemistry and Toxicology. Appointed.
2022 - 2025 Member, Document Development Committee, Clinical and Laboratory Standards Institute (CLSI), CLSI EP21/EP46, Total Analytical Error. Appointed.
2019 - 2024 Member, College of American Pathology Accuracy Based Programs Committee. Appointed.
Recent Invited Presentations
2026 Verifying Comparability of Patient Results Across One Health Care System & Evaluating Reagent Lot-to-Lot Acceptability. College of Physicians and Surgeons of British Columbia, Vancouver BC, Canada.
2024 Embracing New Quality Specifications: Adjusting Lab Practices - CLIA 2024 and Beyond. Evaluating the Impact of an Out-of-Control Event. Association for Diagnostics and Laboratory Medicine (ADLM) Annual Meeting, Chicago, IL.
2023 LC-MSMS 101: Getting Started with Quantitative LC-MS/MS in the Diagnostic Laboratory (4-day workshop). Virtual Short Course
2022 Albumin Harmonization: Impact on Serum, Urine, and Body Fluid Interpretation. American Association for Clinical Chemistry (AACC) Annual Scientific Meeting, Chicago, IL.
2022 CLSI EP26, User Evaluation of Acceptability of a Reagent Lot Change, Clinical and Laboratory Standards Institute, Internationally broadcast webinar
2022 Perspectives on Quality Control Challenges in the Clinical Laboratory. American Association for Clinical Chemistry (AACC) Annual Scientific Meeting, Chicago, IL.
2021 Best Practices to Recover from an Out-of-Control Event, Bio-Rad Quality Control Conference, National Webinar
Selected Publications
Peer Reviewed Papers
Miller WG, Seegmiller JC, Bachmann LM, Pateghini M. Measuring urine albumin and total protein. Nephrol Dial Transplant. 2026 March 19. https://doi.org/10.1093/ndt/gfag060. Epub ahead of print.
Beasley-Green A, Camara JE, Wood ESC, Heckert NA, Miller WG, Bachmann LM, Ruvuna L, Ali S, Schneider R, O'Donnell S, Murrell L, Dai J, Xiong Y, Mahmoud S, Fanto-Holdaway P, Eichler K, Grebe A, Snyder J, O'Brien J, Phinney K. Commutability assessment of NIST SRM 3666 albumin and creatinine in frozen human urine among routine clinical laboratory measurement procedures. Clin Chim Acta. 2025;581:120760.
Bachmann LM. Commentary on Fluctuating hyperparathyroidism after Surgery. [Commentary]. J of Appl Lab Med, 2025;10(6):1713-1714.
Campbell MR, Astles JR, Bachmann LM, Brun M, Bryksin J, Erdosy M, Galior K, Holland M, Jennings B, Kondratovich M, Ladwig P, Love S, Antonio Pereira PA, Yundt-Pacheco J. Evaluation of Total Analytical Error for Quantitative Medical Laboratory Procedures. 3rd Ed. CLSI Guideline EP21. Clinical and Laboratory Standards Institute, USA; 2025
Miller WG, Beasley-Green A, Bachmann LM, Budd J, Tan HT, Teo TL, Liu Q, Phinney KW, Shiba S, Seegmiller J. Extent of equivalence of results for urine albumin among three candidate mass spectrometry reference measurement procedures. Clin Chem, 2024; 70(11):1375-1382
Seegmiller JC, Bachmann LM. Urine Albumin Measurements in Clinical Diagnostics [Review]. Clin Chem. 2024; 70(2):382-391
Williams GW, Downs JW, Wolf CE, Cumpston KL, Tobarran N, Wills BK, Bachmann LM. Evaluation of Strontium Interference in Calcium Measurement Procedures and Content in Supplements as Measured by ICP-MS. JALM. 2023;8(2):307-318
DeVore K, Holland M, Bachmann LM, Chromczak JG, Crepet F, Duncan J, Fennell S, Fertey J, Meng QH, Pierson-Perry JF, Pistorino M, Renley R, Simmons VL, Tusneem NA, Varlan AR, Xiong K. CLSI. Evaluation of Stability of In Vitro Medical Laboratory Test Reagents. 2nd ed. CLSI Guideline EP25. Clinical and Laboratory Standards Institute; 2023
Johansen JV, Bachmann LM, Babic N, D’Agostino PM, Danilenko U, Durham AP, Goldford MD, Long IS, Miller WG, Person NB, Standord JE, Vandepoele N, Varlan AR. Clinical and Laboratory Standards Institute (CLSI).User Evaluation of Acceptability of a Reagent Lot Change, 2nd Edition. CLSI guideline EP26. Clinical and Laboratory Standards Institute, USA, 2022
Clarke W, Molinaro RJ, Bachmann LM, Botelho JC, Cao Z, French D, Garg S, Gawoski JM, Grant RP, Hoofnagle AN, Iyer Bagyalakshmi, Kulasingam V, Mason DS, Rappold B, Tacker DH, Truscott SM, Yu Chunli, Zhu Yusheng. Clinical and Laboratory Standards Institute (CLSI). Liquid Chromatography-Mass Spectrometry Methods, 2nd Edition. CLSI guideline C62. Clinical and Laboratory Standards Institute, USA, 2022
Bystrom C, Grant RP, Bachmann LM, DeMarco M, Holmes DT, Hoofnagle AN, Intelmann D, Jeffery D, Kushnir MM, Ladwig P, Lowenthal MS, Master SR, Shuford CM, Thomas S, Whiteaker J. Clinical and Laboratory Standards Institute (CLSI). Quantitative Measurement of Proteins and Peptides by Mass Spectrometry. 1st ed. CLSI guideline C64. Clinical and Laboratory Standards Institute; 2021
Book Chapters and Monographs
Bachmann LM, French D, van der Gugten JG, Hubbard JA. Quality Assurance for LC-MS/MS Measurement Systems. In: Zhang YV, Garg U, eds. Practical Guide to Implementing Liquid Chromatography Mass Spectrometry in Clinical Laboratories. Springer; 2025.
Bachmann LM, Miller GW. Principles of spectrophotometry and related photometric measurements. In: Clarke W, Dufour RD, eds. Contemporary Practice in Clinical Chemistry. Fourth edition. Washington D.C.: AACC Press. 2020:119-133
Cook JC, Bachmann LM, French D. Steroid Hormones. In: Nair H, Clarke W, eds. Mass Spectrometry for the Clinical Laboratory. First edition. Cambridge: Elsevier Inc, 2017:205-226
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