Dmitry Lyalin, PhD
Molecular Diagnostics
Clinical Assistant Professor
Associate Director of Cytogenetics/Molecular Diagnostics
Department: Pathology
Phone: (804) 628-4886
Email: Dmitry.Lyalin@vcuhealth.org
Dr. Dmitry Lyalin is a board-certified clinical laboratory geneticist, and earned his PhD in Genetics from Texas A&M University. Following his PhD, he worked as a post-doctoral scientist in the NCI-supported preclinical program at Nationwide Children’s Hospital in Columbus, OH, where he evaluated therapeutic agents against childhood solid tumors and leukemias. He then, completed a 3-year American Board of Medical Genetics and Genomics (ABMGG) fellowship at Children’s Mercy Hospital in Kansas City, MO.
Dr. Lyalin is board-certified in Clinical Cytogenetics and Clinical Molecular Genetics and Genomics. After completing the fellowship program, he joined the Sanford Imagenetics Initiative, and helped launch the Sanford Precision screening program. After Sanford, he served as a co-director of the Medical Genetics laboratory at Wake Forest Baptist Medical Center.
Dr. Lyalin joined the VCU Department of Pathology in July 2023 as the Associate Director of the Cytogenetics and Molecular Diagnostics laboratories. His clinical, and research interests include genetic testing for inherited and acquired conditions and the implementation of precision medicine in population health.
Clinical Specialties: Clinical Cytogenetics and Clinical Molecular Genetics and Genomics
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Dr. Dmitry Lyalin abbreviated CV
Education
BS, MSc, Moscow State University, Russia
PhD, Texas A&M University
ABMGG Fellowship, Children’s Mercy Hospital
Licenses & Certifications
2017 American Board of Medical Genetics and Genomics, Clinical Cytogenetics
2019 American Board of Medical Genetics and Genomics, Clinical Molecular Genetics
Recent Invited Presentations
“Implementation of precision medicine in population health” Chapel Hill, NC, October 2024
Selected Publications
Peer Reviewed Papers
Galdon G., Pourhabibi Zarandi N., Deebel, N., Zhang, S., Cornett, O., Lyalin, D., Pettenati, M., Lue Y., Wang, C., Swerdloff, R., Shupe, T., Bishop, C., Stogner, K., Kogan, S., Howards, S., Atala, A., and Sadri-Ardekani, H. “In vitro Generation of Haploid Germ Cells from Human XY and XXY Immature Testes in a 3D Organoid System”, Bioengineering 2024, 11, 677
Lyalin, D., Romanov, Y., “A de novo interstitial 19q13.12q13.32 duplication: Report of a novel patient and literature review”, Genetics in Medicine, 2024, 101632, P728
Fenu E, Beaty M, Insuasti-Beltran G, Pettenati M, Lyalin D “A Unique Case of der(16)t(1;16) Identified in B-Lymphoblastic Leukemia”, Atlas Genet Cytogenet Oncol Haematol. 2021-10-27
Repnikova E, Lyalin D, McDonald K, et al., “CNTN6 copy number variations: Uncertain clinical significance in individuals with neurodevelopmental disorders”, European Journal of Medical Genetics, 2020 Jan;63(1):103636
Roberts J, Lyalin D, Tosatto N, Rana P, Fadoul H, Welsh H, Zhang L, Cooley L, Repnikova E “Novel mosaic SRY gene deletions in three newborn males with variable genitourinary malformations”, Am J Med Genet A. 2018 Jul 28
Posters/Abstracts
“Chimerism in DNA of saliva, buccal, urine and eyebrow specimens from pediatric recipients after allogeneic hematopoietic stem cell transplantation (aHSCT): implication for DNA-based molecular testing”, AMP Annual Meeting, Vancouver, Canada, November 2024
“Unusual Glomerular Abnormalities in a Patient with Combined COL4A5-NPHS1 Variants”, American Society of Nephrology, Kidney Week 2024, October 2024
“The Sanford Health Preemptive Genetic Screening Program - Allele Frequencies for Recurrent variants in CDC Tier 1 Diseases, CYP2C19, and Others”, ACMG 2020 Annual Meeting, San-Antonio, TX
“The Sanford Health Preemptive Genetic Screening”, ACMG 2019 Annual Meeting, Seattle, WA, April 2019
“First Report of Loss of Function in MID2: A Case of MID2-Related X-linked Intellectual Disability”, ACMG 2018 Annual Meeting, Charlotte, NC, April 2018
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