Grace R. Williams, PhD

Toxicology & Chemistry

Grace R. Williams, PhDAssistant Professor; Director of Toxicology Lab

Department: Pathology

Phone: 804-828-3684

Email: grace.r.williams@vcuhealth.org

Grace Williams, PhD, obtained her PhD from the Medical University of South Carolina department of Pharmacology and Experimental Therapeutics. This was followed by a Clinical Chemistry Fellowship at Dartmouth Health.  Dr. Williams has performed research in toxicology, pharmacogenomics, proteomics, and clinical laboratory test interferences. Dr. Williams has knowledge and experience in the fields of drugs of abuse, therapeutic drug monitoring, clinical laboratory testing, mass spectrometry, and pharmacogenomics.

Clinical Specialties: Toxicology, Clinical Chemistry, Drugs of abuse, therapeutic drug monitoring, clinical laboratory testing, mass spectrometry


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Dr. Grace Williams Abbreviated CV

Education

2006-2010   Bachelor of Arts, Department of Chemistry. University of North Carolina at Asheville. Asheville, NC.

2012-2017   Doctorate of Philosophy, Department of Pharmacology and Experimental Therapeutics. Medical University of South Carolina, Charleston, SC.

2017-2019   ComACC Clinical Chemistry Fellow. Dartmouth-Hitchcock Medical Center, Lebanon, NH.

Licenses & Certifications

2021            Diplomat of the American Board of Clinical Chemistry (DABCC)

2024            Fellow of the Academy of Diagnostic and Laboratory Medicine (FADLM)

Professional Service (outside)

Association for Diagnostics & Laboratory Medicine

  • 2024 Chairperson of the Capital Section

Clinical and Laboratory Standards Institute (CLSI)

  • Member- Pre-Examination Processes Expert Panel,
  • Chair-holder- Document Development Committee EP:37 Supplemental Tables for Interference Testing in Chemistry.

International Federation of Clinical Chemistry and Laboratory Medicine

  • Member: Workgroup for Commutability in Metrological Traceability (WG-CMT)

Selected Publications

Peer Reviewed Publications

Williams GR, Poklis JL, Medrano F, and Wolf CE. Detection of 58 Fentanyl Analogs using Lin Zhi and Immunalysis HEIA Fentanyl Immunoassays. 2024. (In preparation)

Williams GR and Bachmann, LE. Interference of Ascorbate in Clinical Chemistry Assays. 2024. (In preparation)

Wolf CE, Pokhai AA, Poklis JL, Williams GR. The Cross Reactivity of Cannabinoid Analogs (Delta-8 THC8- THC, Delta-10 THC10-THC and CBD), and their metabolites, and Chiral Carboxy HHC metabolites in Urine of Six Commercially Available Homogeneous Immunoassays. J Anal Toxicol 2023; doi: 10.1093/jat/bkad059.

Pokhai AA, Poklis JL, Williams GR, Wolf CE. Preanalytical Stability of Emerging Cannabinoid Analogs (Delta-8 THC and Delta-10 THC) and their Metabolites in Urine. J Anal Toxicol 2023 doi: 10.1093/jat/bkad061.

Williams GR, Akala Modesola, and Wolf CE. Detection of 58 Fentanyl Analogs using ARK Fentanyl II and Immunalysis Fentanyl Immunoassays. Clin Biochem 2023;113:45-51. doi: 10.1016/j.clinbiochem.2023.01.001.

Williams GR, Downs JW, Wolf CE, Cumpston KL, Tobarran N, Wills BK, Bachmann M, Evaluation of Strontium Interference in Calcium Measurement Procedures and Content in Supplements as Measured by ICP-MS. J Appl Lab Med 2023;8(2):307-318. doi: 10.1093/jalm/jfac092

Williams GR, Tsongalis GJ, Lewis LD, Barney RE, Cook LJ, Geno KA, Nerenz RD, Potential Impact of Pharmacogenomic Single Nucleotide Variants in a Rural Caucasian Population, J Appl Lab Med 2023;8(2):251-263. doi: 10.1093/jalm/jfac091.

Provost RG, Downs JW, Wolf CE, and Williams GR; The high cost of low quality: Recurring hypoglycemia in a 63-yo man. Clin Chem 2021;67(11):1450-1454. doi: 10.1093/clinchem/hvab174.

Downs JW, Wolf CE, Williams GR, Cumpston KL, Kershner E, and Wills BK, Negligible Nux Vomica: Homeopathic Nux Vomica Remedies Don’t Contain any Strychnine? Toxicon 2021;200:1-2. doi: 10.1016/j.toxicon.2021.06.014

Williams GR, Cook L, Lewis LD, Tsongalis GJ, Nerenz RD. Clinical Validation of a 106-SNV MALDI-ToF MS Pharmacogenomic Panel. J Appl Lab Med. 2020;5(3):454-466. doi: 10.1093/jalm/jfaa018.

Book Chapters and Monographs

Williams GR and Wolf CE. Fentanyl Contamination in Street Drugs. Clinical and Forensic Toxicology News. Mar 2023. (Quarterly, the Association for Diagnostics & Laboratory Medicine (formerly AACC)/CAP), pages. Available from 

Williams GR and Downs JW. Magnesium. Patty's Industrial Hygiene and Toxicology (7th edition) (In publishing - Accepted 2023)

Williams GR, What operational procedures are essential for clinical laboratory infrastructure standardization? AACC Academy Scientific Short, December 2022.


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